@University of Manchester

/ Resources

Open science.

All sequencing data, image analysis pipelines, and protocols are released openly. Explore the resources below, and get in touch if you'd like to re-use or extend any of them.

Datasets & networks

Interactive viewers and deposited datasets from our work on neural crest gene regulatory networks and early chick development.

Protocols

Detailed experimental protocols for working with chick embryos, chromatin profiling, and enhancer screening.

Enhancers

Cis-regulatory elements and enhancers underlying neural crest and placode development — tools, screens, and resources for studying enhancer activity in vivo.

Snai2 (enh13) reporter activity in chick embryos from 6 to 10 somite stages, with NC1 Cherry co-labelling — Snai2 (enh13) reporter activity across 6–10ss, co-labelled with NC1 Cherry.

Lmo4 (enh15) reporter activity in chick embryos from 6 to 12 somite stages — Lmo4 (enh15) reporter activity across 6–12ss.

Lmo4 (enh17) reporter activity in chick embryos from 6-7 to 10 somite stages — Lmo4 (enh17) reporter activity across 6–7ss to 10ss.

Sox10 (enh83) reporter activity in chick embryos from 3-4 to 10 somite stages — Sox10 (enh83) reporter activity across 3–4ss to 10ss.

Tfap-2a (enh78) reporter activity in chick embryos at 9 and 12 somite stages — Tfap-2a (enh78) reporter activity at 9ss and 12ss.

Sox10 (enh84) reporter activity in chick embryos from 4 to 11 somite stages, with enh99 co-labelling at 11ss — Sox10 (enh84) reporter activity across 4–11ss, with Sox10 (enh99) co-labelled at 11ss.

Sox10 (enh87) reporter activity in chick embryos from 8 to 12 somite stages — Sox10 (enh87) reporter activity across 8ss to 12ss.

Sox10 (enh99) reporter activity in chick embryos from 3 to 11 somite stages — Sox10 (enh99) reporter activity across 3ss to 11ss.

FoxD3 (enh193) reporter activity in chick embryos from 6 to 11 somite stages — FoxD3 (enh193) reporter activity across 6ss to 11ss.

Tfap-2a (enh224) reporter activity in chick embryos at 7 and 12 somite stages, with 10x and 5x cranial views — Tfap-2a (enh224) reporter activity at 7ss and 12ss, with higher-magnification cranial views.

Tfap-2a (enh429) reporter activity in chick embryos at HH7 and 10 somite stages — Tfap-2a (enh429) reporter activity at HH7 and 10ss.

Plxna4 (enh415) reporter activity in chick embryos at 9 and 11 somite stages — Plxna4 (enh415) reporter activity at 9ss and 11ss.

Pax3 (enh382) reporter activity in chick embryos from 6 to 12 somite stages — Pax3 (enh382) reporter activity across 6ss to 12ss.

Zic1 (enh373a) reporter activity in chick embryos from 7 to 10 somite stages — Zic1 (enh373a) reporter activity across 7ss to 10ss.

Zic1 (enh373b) reporter activity in chick embryos from 6 to 8 somite stages — Zic1 (enh373b) reporter activity across 6ss to 8ss.

Sox9 (enh366) reporter activity in a chick embryo at the 11 somite stage — Sox9 (enh366) reporter activity at 11ss.

Snai2 (enh370a) reporter activity in chick embryos at 7, 9 and 10 somite stages — Snai2 (enh370a) reporter activity at 7ss, 9ss and 10ss.

FoxD3 (enh372) reporter activity in chick embryos from 6 to 10 somite stages with NC1 Cerulean and NC1 Cherry co-labelling — FoxD3 (enh372) reporter activity across 6ss to 10ss, co-labelled with NC1 Cerulean and NC1 Cherry.

Sox9 (enh349) reporter activity in chick embryos from 3 to 12 somite stages — Sox9 (enh349) reporter activity across 3ss to 12ss.

Robo1 (enh331) reporter activity in chick embryos at 10 and 12 somite stages — Robo1 (enh331) reporter activity at 10ss and 12ss.

Ets1 (enh259) reporter activity in chick embryos at 6, 8-9 and 10 somite stages — Ets1 (enh259) reporter activity at 6ss, 8–9ss and 10ss.

Snai2 (enh239) reporter activity in chick embryos from 7 to 11 somite stages — Snai2 (enh239) reporter activity across 7ss to 11ss.

Snai2 (enh241) reporter activity in chick embryos at 3-4 and 9 somite stages — Snai2 (enh241) reporter activity at 3–4ss and 9ss.

Snai2 (enh242) reporter activity in chick embryos at 8 somite stage (dorsal and ventral) and 10 somite stage — Snai2 (enh242) reporter activity at 8ss (dorsal and ventral views) and 10ss.

Snai2 (enh334) reporter activity in chick embryos from 4 to 10 somite stages — Snai2 (enh334) reporter activity across 4ss to 10ss.

Pax6 (enh309) reporter activity in chick embryos at 7-8 and 10 somite stages — Pax6 (enh309) reporter activity at 7–8ss and 10ss.

Cdh13 (enh325) reporter activity in chick embryos at 6 and 9 somite stages — Cdh13 (enh325) reporter activity at 6ss and 9ss.

Cdh6 (enh318) reporter activity in chick embryos at 6, 8-9, 8 and 10 somite stages — Cdh6 (enh318) reporter activity at 6ss, 8–9ss, 8ss and 10ss.

Snai2 (enh332) reporter activity in chick embryos from 7 to 10 somite stages — Snai2 (enh332) reporter activity across 7ss to 10ss.

Tfap-2b (enh338) reporter activity in chick embryos at 6, 8 and 9 somite stages — Tfap-2b (enh338) reporter activity at 6ss, 8ss and 9ss.

Sox9 (enh344) reporter activity in chick embryos at 6, 6-7 and 10 somite stages — Sox9 (enh344) reporter activity at 6ss, 6–7ss and 10ss.

Sox9 (enh345) reporter activity in chick embryos at 6-7, 7, 7-8 and 10 somite stages — Sox9 (enh345) reporter activity at 6–7ss, 7ss, 7–8ss and 10ss.

Tfap-2b (enh226) reporter activity in chick embryos at 8 and 10 somite stages — Tfap-2b (enh226) reporter activity at 8ss and 10ss.

Sox8 (enh279) reporter activity in a chick embryo at the 7-8 somite stage — Sox8 (enh279) reporter activity at 7–8ss.

Tfap-2a (enh249) reporter activity in chick embryos at 5, 7 and 8 somite stages — Tfap-2a (enh249) reporter activity at 5ss, 7ss and 8ss.

Pax3 (enh273) reporter activity in chick embryos at 6, 8, 9-10 and 11 somite stages — Pax3 (enh273) reporter activity at 6ss, 8ss, 9–10ss and 11ss.

Sox9 (enh283) reporter activity in chick embryos at 6, 7, 9 and 10 somite stages — Sox9 (enh283) reporter activity at 6ss, 7ss, 9ss and 10ss.